ED

PDE5 inhibitors (tadalafil, sildenafil), daily-dose strategies, cardiac safety, and when these medications are not appropriate.

Tadalafil vs Sildenafil: Which PDE5 Inhibitor Is Right for You?

Tadalafil and sildenafil are the two most prescribed PDE5 inhibitors for erectile dysfunction. They share a mechanism but differ meaningfully in onset, duration, food sensitivity, and dosing flexibility. Here is the clinician-reviewed comparison.

Apr 25, 2026

Daily-Dosing Tadalafil: Pros and Cons of the Low-Dose Approach

Low-dose daily tadalafil is FDA-approved for ED and BPH, and is the only PDE5 inhibitor with an approved daily dosing schedule. Here is when daily dosing makes sense, when it does not, and what to expect.

Apr 25, 2026